张帅兵，自然科学博士，蘑菇视频 教授，博士生导师，国家高层次青年人才项目、“江苏省特聘教授”（2025）获得者。2017年硕士毕业于中国科学院昆明植物研究所，师从刘吉开教授；2022年博士毕业于德国莱布尼兹天然产物与感染生物学研究所，师从 Pierre Stallforth 教授；2022-2025年继续在德国莱布尼兹天然产物与感染生物学研究所从事博士后研究。2026年4月全职加入蘑菇视频 ，成立微生物互作与生物合成课题组。近年来围绕微生物互作与天然产物功能机制开展系统研究，在该领域发表了一系列高水平研究成果，相关论文发表于Cell、PNAS、JACS、Angew Chem等国际权威期刊。

我们课题组关注天然产物的发现、生物合成机制、微生物相互作用以及化学生物学及生态学功能。

主持的经费：

蘑菇视频 高层次人才科研启动经费

国家高层次青年人才经费

江苏省特聘教授科研经费

代表性成果：

1. S. Zhang, Y. Huang, K. Schlabach, M. A. Tran, R. Nachawati, N. Bader, A. J. Komor, C. Hertweck, H. Schindelin, M. Lakemeyer,* U.A. Hellmich,*and P. Stallforth* “Microbial DL-Peptidases Enable Predator Defense and Facilitate Structure Elucidation of Complex Natural Products. ” J. Am. Chem. Soc. 2026, 148, 5264-5274. (SI Cover article)

2. S. Zhang, K. Schlabach, V. H. Pérez Carrillo, A. Ibrahim, Shahran Nayem, A. Komor, R. Mukherji, S. Chowdhury, L. Reimer, A. Corina Volt, C. Hertweck, U. A. Hellmich, P. Stallforth* “Pathogenic bacteria use a chemical radar to detect and destroy the predators” Cell, 2025, 188, 2495 – 2504.

3. S. Zhang, Y. Huang, R. Nachawati, P. Huber, G. Walther, L. Grefor, I. Vilotigevic, P. Stallforth* “Pangenome analysis for the plant pathogen Pseudomonas syringae reveals unique natural products for niche adaptation” Angew. Chem. Int. Ed. 2025, 64, e202503679.

4. S. Zhang, P. Stallforth* “Biofilms and exopolysaccharides in Pseudomonas aeruginosa: pathogenesis, immune evasion, and lung–brain signaling during pneumonia”. Signal Transduc. Target Ther., 2024, 9, 204.

5. S. Zhang+, R. Mukherji+, S. Chowdhury, L. Reimer, P. Stallforth* “Lipopeptide-mediated bacterial interaction enables cooperative predator defense” Proc. Natl. Acad. Sci. U. S. A. 2021, 118, e2013759118. (Cozzarelli Prize Winner 2022)

6. R. Mukherji+, S. Zhang+, S. Chowdhury, P. Stallforth* “Chimeric LuxR transcription factors rewire natural product regulation” Angew. Chem. Int. Ed. 2020, 59, 6192–6195.

7. S. Zhang, Y. Huang, H. Chen, Z. Li, B. Wu, T. Feng*, J. Liu* “Confluenines A–F, N-oxidized l-isoleucine derivatives from the edible mushroom Albatrellus confluens” Tetrahedron lett. 2018, 59, 3262-3266.

8. S. Zhang, Z. Li, M. Stadler, H. Chen, Y. Huang. X. Gan, T. Feng*, J. Liu* “Lanostane Triterpenoids from Tricholoma pardinum with NO Production inhibitory and cytotoxic activities” Phytochemistry 2018, 152, 105-112.

9. S. Zhang, Y. Huang, S. He, H. Chen, B. Wu, S. Li, Z.Zhao, Z. Li, X. Wang, J. Zuo*, T. Feng*, J. Liu* “Heterocyclic compounds from the mushroom Albatrellus confluens and their inhibitions against lipopolysaccharides-induced B lymphocyte cell proliferation” J. Org. Chem. 2018, 83, 10158-10165. (Hot off the press in Natural Product Reports)

10.S. Zhang, Y. Huang, S. He, H. Chen, Z. Li, B Wu, J. Zuo, T. Feng*, J. Liu* “Albatredines A and B, a pair of epimers with unusual natural heterocyclic skeletons from edible mushroom Albatrellus confluens” RSC Adv. 2018, 8, 23914-23918. (Hot off the press in Natural Product Reports)

1. medac Research Award, 2026, 德国medac公司

2. PhD award from Friedrich Schiller University, 2024, 德国耶拿大学

3. medac Research Award, 2024, 德国medac公司

4. VAAM PhD Award, 2023, 德国应用微生物协会

5. The Cozzarelli Prize, 2022, 美国科学院

6. medac Research Award, 2022, 德国medac公司

7. 国家优秀自费留学生奖学金, 2021, 中国教育部

8. medac Research Award, 2020, 德国medac公司

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