蘑菇视频

李桢
教授博士生导师

电话:邮箱:[email protected]

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研究领域:心脑血管病理、生理、药理

招生方向:中药学,中药学-中药药理与临床中药学,中药-中药药效与安全性评价

  • 个人简介
  • 教学与课程
  • 研究方向
  • 项目与成果
  • 奖励荣誉
  • 教材或专著
  • 课题组介绍
  • 主持项目:

    国家自然科学基金优秀青年科学基金项目

    国家自然科学基金青年科学基金项目C类


    代表性论文:

    1. Li Zet al. Dysregulated Protein s-Nitrosylation Promotes Nitrosative Stress and Disease Progression in Heart Failure with Preserved Ejection Fraction. Circulation Research. Oct 2025.

    2. Li Zet al. Alcohol-induced Gut Microbial Reorganization and Associated Overproduction of Phenylacetylglutamine Promotes Cardiovascular Disease. Nature Communications. Dec 2024.

    3. Li Zet al. Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart Failure. Circulation Research. Jan 2023.

    4. Li Zet al.  Mitochondrial H2S Regulates BCAA Catabolism in Heart Failure. Circulation Research. Jul 2022.

    5. Xia H and Li Zet al. Endothelial Cell Cystathionine γ-Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury. Journal of American Heart Association. Oct 2020

    6. Organ Cand Li Zet al. Nonlethal inhibition of gut microbial trimethylamine N-oxide production improves cardiac function and remodeling in a murine model of heart failure. Journal of American Heart Association. May 2020

    7. Li Z,et al. Hydrogen Sulfide Attenuates Renin Angiotensin and Aldosterone Pathological Signaling and Improves Exercise Tolerance in Heart Failure. JACC: Basic to Translational Science. Dec 2018

    8. Li Zet al. Evolution of Hydrogen Sulfide Therapeutics to Treat Cardiovascular Disease. Circulation Research. Aug 2018.

    9. ZhengY, YuB, and Li Zet al. A Novel Esterase-sensitive Prodrug Approach for Controllable Delivery of Persulfide Species. Angewandte Chemie. 2017

    10.Kang J and Li Z et al. pH-Controlled Hydrogen Sulfide Release for Myocardial Ischemia-Reperfusion Injury. Journal of the American Chemical Society. May 2016.


  • 热忱欢迎有志于开展学科交叉研究的同学报考(如病理生理学、流行病学、细胞/分子生物学、生物信息学等)!